Endocrine Abstracts

Introduction: Renal impairment associated with hypothyroidism without any other clear underlying cause is relatively rare. We report a case with severe hypothyroidism admitted with acute renal failure.Case report: A 72 years old female patient was addmitted to the emergency department with progressively worsening complaints of fatigue, somnolence, and swellings all over her body for the last 3 weeks. Initial laboratory examination revealed acute renal fa...

Objectives: Ultrasound-guided fine needle aspiration biopsy (US-FNAC) technique has the advantage of obtaining tissue for cytological examination. The diagnostic yield may depend on factors related to both technical aspects and the lesions sampled. However, the variability between experienced and inexperienced physicians in obtaining adequate cytological sample has not been specifically studied previously. The aim of the study was to determine whether there is a difference in ...

Objective: The evidence regarding association between thyroid diseases and benign and malign breast diseases is increasing. It has been shown that thyroid disorders are more frequent in those with benign breast diseases and that different thyroid diseases have associations with benign and malign breast diseases and their outcomes. In this study, we aimed to reveal the frequency of benign breast conditions in patients with nodular thyroid disease and Hashimoto’s disease.</...

Introduction: Orthorexia (nervosa) is an eating disorder, characterised by an obsession with avoiding foods perceived to be unhealthy. Though it has not been recognised as a pathological entity in Diagnostic and Statistical Manual of Mental Disorders – IV yet, interest in the condition has increased recently. This study aimed to determine the prevalence and risk factors of orthorexia in a group of diabetic patients.Methods and design: 134 (63 female...

Proton pump inhibitor (PPI) drugs which are used safely to treat peptic ulcus disease since 2 decades, moderately increases gastrin hormone by decreasing gastric acid secretion. Preclinical studies show that gastrin itself, or drugs that increase gastrin levels such as PPIs, increase islet cell mass and improve glycaemic control. To the best of our knowledge one prospective and some retrospective studies claim that PPI medication in diabetic patients leads to an average decrea...

Introduction: The risk of malignancy has often been reported to be more frequent in Graves’ disease (GD) than non-autoimmune thyroid nodules. However, frequency of thyroid nodules, diagnostic yield of fine-needle aspiration (FNA), and their potential for bearing malignancy in GD are still debatable issues. We aimed to determine the prevalence, ultrasonographic and cytological features, and the rate of malignancy outcome of thyroid nodules in a group of patients with GD.</...

While statins which are used safely to treat dyslipidemia, and improve cardiovascular mortality, recent articles claim that they also impairs glycaemic control in type 2 diabetes patients. Meta-analysis of larger scale studies indicate that use of statins is associated with an increase of 9% in diabetes onset. Despite that, we know not much about their effect on glucose regulation in patients already diagnosed with diabetes. Therefore, we aimed to investigate the effect of sta...

Introduction: Previous reports have shown that subjects with insulin resistance have increased thyroid volume and nodule prevalence. We investigated the effects of metformin on thyroid volume and nodule size.Methods: This prospective data were gathered on newly diagnosed subjects with insulin resistance (n=100, 68 female, 32 male) between August 2008 and May 2010. Measurements of thyroid hormones and thyroid ultrasonography was performed in all ...

Introduction: There is accumulating evidence on the favourable effects of some statins on bone and mineral metabolism. Although some studies have reported drop of serum 25-hydroxyvitamin D levels in subjects receiving statin therapy, comparative studies evaluating various statins in prospective randomized design is lacking. Our purpose is to compare the effects of variable doses of rosuvastatin and atorvastatin on serum 25-hydoxyvitamin D levels adjusted for seasons.<p cla...

Objective: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities with insulin resistance (IR) as a major characteristic. It has been recently questioned that MetS and its related components are associated with functional and morphological alterations of thyroid gland. Aim of our study is to examine thyroid volume and nodule prevalence in patients with MetS in a mild-to-moderate iodine deficient area.Design: Two hundred and seventy-eight p...